The Science

SmartZYME™ is a "game changer" in DHA Omega 3 pet nutrition.

Stop feeding harmful fish oil. Feed your pet SmartZYME™ to get DHA fresh from its source!

You may already know the health benefits of Omega-3 and why DHA is the most important fatty acid. It’s been shown to improve and even prevent many chronic health issues including heart disease, inflammation, asthma, arthritis, and certain cancers, just to name a few.

-Benefits of DHA in mammals

However, our bodies do not produce nearly enough DHA to satisfy the demand within our cells. The DHA we require to function properly must come from food or supplements such as fish oil.

But fish oil is an imperfect solution to providing this critical nutrient. To extract the oil from fish requires heat, heat destroys the metabolic enzymes that algae possess to produce additional DHA. And, extracted fish oil is extremely prone to damaging oxidation. Once the package is opened, fish oil oxidizes quickly and spoils, often long before the expiration date. Oxidized fish oil is toxic and is very bad for people and pets who consume it.

  •  Albert, B. et al. (2013). “Oxidation of Marine Omega-3 Supplements and Human Health”. Biomedicine Research International. Vol. 2013.
  • Albert, B. et al. (2015). “Fish oil Supplements in New Zealand are Highly Oxidized and Do Not Meet Label Content of n-3 PUFA”. Scientific Reports. Vol. 5(1):7928.

Fish get DHA from eating ocean algae, but the extraction process to make Omega 3 oil is fraught with problems. SmartZYME™ delivers the most natural, bioavailable DHA nutrition directly from the source: ocean algae and without all the problems.

Why Choose SmartZYME™?

All Natural

SmartZYME™ is grown from 100% all natural, non-GMO ingredients. Contains NOTHING synthetic or artificial and has no fillers.


SmartZYME™ is brined to preserve its natural freshness. SmartZYME™ is the only Omega 3 product to deliver highly bio-available DHA, complete with active DHA producing enzymes.


SmartZYME™ is sustainably-grown and organic Golden Algae

Grain Free

SmartZYME™ is grain free and does not contain any of the glutens that can trigger allergic reactions.

Made in the USA

SmartZYME™ is sustainably grown and cultivated in a contaminant-free environment in Maine.

Developed Specifically for Pets
by a Team of Scientists and Pet Lovers!

Developed Specifically for Pets by a Team of Scientists and Pet Lovers!

SmartZYME™ adds bio-available DHA
directly to your pet’s food.

SmartZYME™ adds bio-available DHA directly to your pet’s food.

  • SmartZYME™ is grown from algae that produces only DHA — the most important Omega 3 fatty acid. SmartZYME™ works to directly convert glucose to (DHA laden) healthy fats. Unlike all other Omega 3 products available, we do not extract oil from the cells, nor do we use damaging heat in any part of our process to make SmartZYME™. SmartZYME™ is natural, whole cell DHA nutrition that uniquely preserves the active DHA producing enzymes. The enzymes work to multiply the amount of DHA in the body and thereby benefit cognition, circulation, mobility, weight management and restore balance to the metabolism.
  • Unlike most DHA products, SmartZYME™ is a fresh, wholesome food that is not processed or chemically extracted and has no added synthetic or artificial ingredients. 
  • SmartZYME™ is produced in a sterile proprietary growing system.
  • The enzymes specific to SmartZYME™ directly convert glucose and fructose to healthy good fats in the body.
  • SmartZYME™ adds the most highly bio-available DHA directly to your pet’s food to improve health, vitality, metabolism, memory and cognition!

SmartZYME™ is the ONLY DHA product available with
ACTIVE DHA producing enzymes!

SmartZYME™ is the ONLY DHA product available withACTIVE DHA producing enzymes!

Read our White Papers to learn why SmartZYMETM  should be a part of your pet’s healthy diet.



  • Fish oil manufacturers use heat in the production process that destroys any of the special enzymes that algae naturally possess, thus limiting the health benefits that might be derived from Omega 3 nutrients. The whole cell DHA nutrition offered by SmartZYME™ is the safer, better solution. Any benefits to brain, heart, and metabolic health derived from Omega 3 extracted oils are therefore vastly limited compared to the whole cell DHA nutrition offered by SmartZYME™.
  • The process to extract Omega 3 fatty acids from fish causes extracted Omega 3 oils to begin to spoil the moment the package seal is broken and the contents are exposed to the air.  Toxic oxidation can begin to occur within weeks; much sooner than the date stamped on the package. The antioxidants added by manufacturers offer little added protection. Once this damaging oxidation process starts there is no going back!

Kolanowski, W., et al. (2006). Microencapsulation of fish oil by spray drying–impact on oxidative stability. Part 1. Eur Food Res Technol 222, 336–342 (2006). 

-Shows increases in fish oil oxidation of both bulk and Microencapsulated fish oil over a 30 day period. The study concludes that it is an acceptable level of oxidation, however, had this study been continued until 90 days, that level may no longer be acceptable. This study mimics a lot of other studies on fish oil oxidation, where the trial period is shorter than the time it takes to consume a 90 day supply of fish oil tablets. This misleads the consumer on the valid shelf life of extracted fish oils. 

  • Oxidized fish oil is toxic and can poison your pet – we advise that you throw it out! Order SmartZYME™, the safer alternative.
micro algae supplements

Articles showing DHA benefits in Pets

  • 5 Reasons To Supplement Your Dog’s Diet With DHA. Amber King.,pup%E2%80%99s%20skin%20isn%E2%80%99t%20dry%2C%20flaky%2C%20and…%20More%20
  • Fritsch, D. et al. (2010). “Dose‐Titration Effects of Fish Oil in Osteoarthritic Dogs”. Journal of Veterinary Internal Medicine. Vol 24. Pg 120-126
  • Freeman, L. M. et al. (1998). Nutritional Alterations and the Effect of Fish Oil Supplementation in Dogs with Heart Failure. Journal of Veterinary Internal Medicine Vol 12. Pages 440-448
  • Bauer, J. (2007).“Responses of Dogs to Dietary Omega-3 Fatty Acids”. Journal of the American Veterinary Medical Association. Vol. 231, No. 11, Pages 1657-1661.
  • Filburn, C., Griffin, D. (2005). “Supplementation with a Docosahexaenoic Acid-Enriched Salmon Oil on Total Plasma and Plasma Phospholipid Fatty Acid Composition in the Cat.” Effects of International Journal of Applied Research in Veterinary Medicine, Vol 3
  • Heinemann, K., Bauer, J. (2006). “Docosahexaenoic Acid and Neurologic Development in Animals.” Journal of the American Veterinary Medical Association, Vol. 228, No. 5, Pages 700-705.
  • Corbee, et al. (2012). The effect of dietary long-chain omega-3 fatty acid supplementation on owner’s perception of behavior and locomotion in cats with naturally occurring osteoarthritis. Journal of Animal Physiology and Animal Nutrition

Articles showing oxidation issues with extracted oil product

  • Ghnimi, S., Budilarto, E., Kamal-Eldin, A. (2017). “The New Paradigm for Lipid Oxidation and Insights to Microencapsulation of Omega-3 Fatty Acids.” Comprehensive Reviews in Food Science and Food Safety. Vol.16, 2017